Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440579 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27440566 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27440574 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441088 | 0.89 | EGFR (0.57) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441075 | 0.89 | EGFR (0.57) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441064 | 0.89 | EGFR (0.57) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441083 | 0.89 | EGFR (0.57) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441079 | 0.84 | KDM4E (0.71) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441062 | 0.82 | PTP4A1 (0.59) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL27441069 | 0.82 | PTP4A1 (0.59) | ALDH1A1MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030877-B2 | Prostaglandin E synthase inhibitors and methods for utilizing the same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030877-B2 | Prostaglandin E synthase inhibitors and methods for utilizing the same | PTGES, PTGS1, PTGES2 | ALDH1A1 474/4885MEN1 4764/4885KMT2A 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.