Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.61 |
| ▸ | APP | P05067 | 7/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440693 | 0.85 | SNCA (0.53) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL24163770 | 0.85 | SNCA (0.62) | SNCAAPPENPP2ALDH1A1HTT | |
| SCHEMBL27440336 | 0.83 | SNCA (0.63) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL27440479 | 0.83 | SNCA (0.53) | SNCAAPPENPP2CNR1CNR2 | |
| SCHEMBL27440660 | 0.83 | APP (0.59) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL27440870 | 0.75 | APP (0.47) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL27440181 | 0.73 | SNCA (0.76) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL27440682 | 0.72 | SNCA (0.56) | SNCAAPPENPP2ALDH1A1CNR1 | |
| SCHEMBL24164332 | 0.72 | APP (0.60) | SNCAAPPENPP2ALDH1A1KDM4E | |
| SCHEMBL27440352 | 0.72 | SNCA (0.58) | SNCAAPPENPP2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |