Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.60 |
| ▸ | SNCA | P37840 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24164296 | 0.89 | APP (0.64) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL27440181 | 0.89 | SNCA (0.76) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL27440345 | 0.89 | APP (0.60) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL27440336 | 0.89 | SNCA (0.63) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL32677383 | 0.88 | APP (0.57) | APPSNCAGLAENPP2ALDH1A1 | |
| SCHEMBL31169581 | 0.88 | APP (0.57) | APPSNCAGLAENPP2ALDH1A1 | |
| SCHEMBL27440358 | 0.88 | SNCA (0.57) | APPSNCAGLAENPP2ALDH1A1 | |
| SCHEMBL25424902 | 0.88 | APP (0.57) | APPSNCAGLAENPP2ALDH1A1 | |
| SCHEMBL27440758 | 0.88 | SNCA (0.57) | APPSNCAGLAENPP2ALDH1A1 | |
| SCHEMBL24164335 | 0.88 | SNCA (0.57) | APPSNCAGLAENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559490-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-24 | — | — | US | disclosed |
| US-20230322765-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-20230322765-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-20230322765-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| WO-2022006040-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322765-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, PDK1 | APP 2860/4885SNCA 4854/4885GLA 1338/4885 |
| US-12559490-B2 | Compositions and methods for modulating hair growth | PC, MTCH2, MPC2 | APP 2307/4885SNCA 4595/4885GLA 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.