Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.56 |
| ▸ | APP | P05067 | 7/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440679 | 0.81 | APP (0.58) | SNCAAPPENPP2ELANEMAPT | |
| SCHEMBL27440345 | 0.81 | APP (0.60) | SNCAAPPENPP2ELANEMAPT | |
| SCHEMBL27440665 | 0.72 | SNCA (0.61) | SNCAAPPENPP2MAPTALDH1A1 | |
| SCHEMBL27440352 | 0.72 | SNCA (0.58) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL24164335 | 0.71 | SNCA (0.57) | SNCAAPPENPP2MAPTALDH1A1 | |
| SCHEMBL27440660 | 0.71 | APP (0.59) | SNCAAPPENPP2MAPTALDH1A1 | |
| SCHEMBL26552290 | 0.70 | SNCA (0.53) | SNCAAPPENPP2ELANEMAPT | |
| SCHEMBL27440336 | 0.70 | SNCA (0.63) | SNCAAPPENPP2MAPTALDH1A1 | |
| SCHEMBL24164332 | 0.70 | APP (0.60) | SNCAAPPENPP2MAPTALDH1A1 | |
| SCHEMBL27440509 | 0.69 | SNCA (0.72) | SNCAAPPENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |