Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | SNCA | P37840 | 6/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440741 | 0.86 | APP (0.52) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL31050165 | 0.83 | APP (0.55) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL27440440 | 0.83 | APP (0.55) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL25773497 | 0.83 | SNCA (0.53) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL27440427 | 0.83 | APP (0.46) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL24164335 | 0.82 | SNCA (0.57) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL27440771 | 0.79 | SNCA (0.54) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL24163776 | 0.75 | APP (0.60) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL27440660 | 0.74 | APP (0.59) | APPSNCAENPP2MAPTTHRB | |
| SCHEMBL31050168 | 0.74 | APP (0.52) | APPSNCAENPP2MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |