Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.57 |
| ▸ | APP | P05067 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24164332 | 0.88 | APP (0.60) | SNCAAPPGLAENPP2ALDH1A1 | |
| SCHEMBL25773497 | 0.84 | SNCA (0.53) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440995 | 0.82 | APP (0.51) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440679 | 0.80 | APP (0.58) | SNCAAPPGLAENPP2ALDH1A1 | |
| SCHEMBL24163776 | 0.80 | APP (0.60) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440660 | 0.79 | APP (0.59) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440633 | 0.79 | APP (0.54) | SNCAAPPGLAENPP2ALDH1A1 | |
| SCHEMBL27440509 | 0.78 | SNCA (0.72) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440345 | 0.78 | APP (0.60) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL24164296 | 0.77 | APP (0.64) | SNCAAPPENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022006040-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |