Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 0.77 |
| ▸ | BACE1 | P56817 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | STAT3 | P40763 | 1/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.65 |
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744098 | 1.00 | F3 (1.00) | F3GSK3BBACE1THRBATM | |
| SCHEMBL14331811 | 1.00 | F3 (1.00) | F3GSK3BBACE1THRBATM | |
| SCHEMBL17837284 | 0.98 | F3 (0.96) | F3GSK3BBACE1THRBATM | |
| SCHEMBL28609815 | 0.93 | F3 (0.86) | F3GSK3BBACE1THRBATM | |
| SCHEMBL5599044 | 0.93 | F3 (0.86) | F3GSK3BBACE1THRBATM | |
| SCHEMBL5599042 | 0.93 | F3 (0.86) | F3GSK3BBACE1THRBATM | |
| SCHEMBL11999799 | 0.93 | F3 (0.86) | F3GSK3BBACE1THRBATM | |
| SCHEMBL10467112 | 0.91 | F3 (0.83) | F3GSK3BBACE1THRBATM | |
| SCHEMBL10467108 | 0.91 | F3 (0.83) | F3GSK3BBACE1THRBATM | |
| SCHEMBL10467105 | 0.91 | F3 (0.83) | F3GSK3BBACE1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390585-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-07-19 | — | — | US | claimed |
| US-20100152493-A1 | BIS(ARYLMETHYLIDENE)ACETONE COMPOUND, ANTI-CANCER AGENT, CARCINOGENESIS-PREVENTIVE AGENT, INHIBITOR OF EXPRESSION OF Ki-Ras, ErbB2, c-Myc AND CYCLINE D1, BETA-CATENIN-DEGRADING AGENT, AND p53 EXPRESSION ENHANCER | SHIBATA, HIROYUKI (JP) | 2010-06-17 | — | — | US | claimed |
| EP-0302832-B1 | THERMOSET COMPOSITIONS CONTAINING UNSATURATED IMIDES AND DERIVATIVES OF BENZALDEHYDE | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | claimed |
| US-4935478-A | Unsaturated imide and benzaldehyde derivative containing hot-curable composition of matter | CIBA-GEIGY CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| EP-0302832-A2 | Thermoset compositions containing unsaturated imides and derivatives of benzaldehyde | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | claimed |
| EP-4731635-A1 | CHIRAL IRIDIUM HYDRIDE CATALYSTS FOR ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2- DIHYDROQUINOLINES | Bayer Aktiengesellschaft (DE) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024261094-A1 | CHIRAL IRIDIUM HYDRIDE CATALYSTS FOR ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2- DIHYDROQUINOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024060641-A1 | CYCLOTRIARYLPHOSPHINE, METHOD FOR PREPARING SAME, AND USE THEREOF | 东莞市均成高新材料有限公司 | 2024-03-28 | — | — | WO | disclosed |
| US-20230098847-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-03-30 | — | — | US | disclosed |
| CN-115850329-A | Cycloterpyriaryl phosphines, their preparation and use | 东莞市均成高新材料有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11390585-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-07-19 | — | — | US | disclosed |
| US-20220213081-A1 | GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-07-07 | — | — | US | disclosed |
| US-4935478-A | Unsaturated imide and benzaldehyde derivative containing hot-curable composition of matter | CIBA-GEIGY CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0302832-A2 | Thermoset compositions containing unsaturated imides and derivatives of benzaldehyde | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | disclosed |
| EP-0160783-B1 | PROCESS FOR ENCAPSULATING AGENTS EXHIBITING A COLOUR ON REACTION, SAID CAPSULES AND THEIR USE IN COLOUR RECORDING SHEETS | Papierfabrik August Koehler AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0160783-A1 | Process for encapsulating agents exhibiting a colour on reaction, said capsules and their use in colour recording sheets | Papierfabrik August Koehler AG (DE) | 1985-11-13 | — | — | EP | disclosed |
| US-4552876-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | USV PHARMACEUTICAL CORP. (US) | 1985-11-12 | — | — | US | disclosed |
| US-4349553-A | Spiro-cyclopropyl amidinohydrazones, and use as insect and fire ant control agents | AMERICAN CYANAMID COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4347232-A | Preparation of hydrogen peroxide from its elements | FMC CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152493-A1 | BIS(ARYLMETHYLIDENE)ACETONE COMPOUND, ANTI-CANCER AGENT, CARCINOGENESIS-PREVENTIVE AGENT, INHIBITOR OF EXPRESSION OF Ki-Ras, ErbB2, c-Myc AND CYCLINE D1, BETA-CATENIN-DEGRADING AGENT, AND p53 EXPRESSION ENHANCER | MYC, CCNE2, CCNE1 | F3 3373/4885GSK3B 1233/4885BACE1 671/4885 |
| US-20220213081-A1 | GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME | GMNN, GRIA1, GRIA2 | F3 4303/4885GSK3B 3139/4885BACE1 129/4885 |
| US-11390585-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | F3 1013/4885GSK3B 1735/4885BACE1 1673/4885 |
| US-20230098847-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | F3 1013/4885GSK3B 1735/4885BACE1 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.