Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415464 | 0.85 | DHODH (0.58) | DAOKDM4EALDH1A1HSD17B10PBRM1 | |
| SCHEMBL2808417 | 0.85 | DHODH (0.58) | DAOKDM4EALDH1A1HSD17B10PBRM1 | |
| SCHEMBL27348185 | 0.81 | DAO (0.64) | DAOKDM4ECA12CA9ALDH1A1 | |
| SCHEMBL9264392 | 0.81 | DAO (0.64) | DAOKDM4EALDH1A1HSD17B10RXFP1 | |
| SCHEMBL9257509 | 0.80 | DHODH (0.47) | DAOKDM4EALDH1A1HSD17B10DHODH | |
| SCHEMBL8817185 | 0.80 | DAO (0.41) | DAOKDM4ECA12CA9ALDH1A1 | |
| SCHEMBL16767858 | 0.78 | DAO (1.00) | DAOCA12CA9HRH4AKR1B1 | |
| SCHEMBL1144741 | 0.78 | HPGD (0.60) | DAOKDM4ECA12CA9ALDH1A1 | |
| SCHEMBL5945907 | 0.77 | CNR2 (0.57) | KDM4ECA12CA9TSHRALDH1A1 | |
| SCHEMBL21639472 | 0.77 | BRD4 (0.46) | DAOKDM4EALDH1A1HSD17B10DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098839-C | Preparation and application of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 2003-01-15 | — | — | CN | disclosed |
| CN-1098839-C | Preparation and application of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 2003-01-15 | — | — | CN | disclosed |
| CN-1098839-C | Preparation and application of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 2003-01-15 | — | — | CN | disclosed |
| CN-1097418-A | The preparation method and its usage of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 1995-01-18 | — | — | CN | disclosed |
| CN-1097418-A | The preparation method and its usage of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 1995-01-18 | — | — | CN | disclosed |
| CN-1097418-A | The preparation method and its usage of 8-chloroquinolone carboxylic acid derivative | LI YONGKANG (CN) | 1995-01-18 | — | — | CN | disclosed |