SCHEMBL2808417

SCHEMBL2808417

O=C(O)c1cc2cccc(C(=O)O)c2[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.58
KEAP1 Q14145 1/20 0.51
KDM4E B2RXH2 3/20 0.45
GAA P10253 2/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
PBRM1 Q86U86 1/20 0.45
CNR2 P34972 1/20 0.45
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
MAPT P10636 1/20 0.44
PIM1 P11309 1/20 0.44
GFER P55789 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
DAO P14920 3/20 0.44
DDO Q99489 2/20 0.44
UCHL1 P09936 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415464 1.00 DHODH (0.58) DHODHKEAP1KDM4EGAAALDH1A1
SCHEMBL9257509 0.88 DHODH (0.47) DHODHKEAP1KDM4EGAAALDH1A1
SCHEMBL9358099 0.86 DAO (0.61) DHODHKEAP1KDM4EALDH1A1PBRM1
SCHEMBL27348185 0.85 DAO (0.64) DHODHKEAP1KDM4EGAAALDH1A1
SCHEMBL9264392 0.85 DAO (0.64) KDM4EGAAALDH1A1HSD17B10HPGD
SCHEMBL27443353 0.85 DAO (0.64) DHODHKDM4EGAAALDH1A1POLB
SCHEMBL3551666 0.81 KDM4E (0.50) DHODHKEAP1KDM4EGAAALDH1A1
SCHEMBL8817185 0.81 DAO (0.41) DHODHKEAP1KDM4EGAAALDH1A1
SCHEMBL5945907 0.81 CNR2 (0.57) KDM4EGAAALDH1A1POLBCNR2
SCHEMBL21639472 0.81 BRD4 (0.46) DHODHKDM4EGAAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 DHODH 823/4885KEAP1 3517/4885KDM4E 2504/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB DHODH 3231/4885KEAP1 2591/4885KDM4E 1615/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA DHODH 1138/4885KEAP1 3371/4885KDM4E 1109/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA DHODH 922/4885KEAP1 3215/4885KDM4E 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.