SCHEMBL27445429

SCHEMBL27445429

c1ccc(-c2cccc(-c3nc(-c4ccc5oc6ccccc6c5c4)nc(-c4cccc5c4oc4ccc6c7ccccc7n(-c7ccccc7)c6c45)n3)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.34
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
CHEK2 O96017 1/20 0.32
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PRKDC P78527 1/20 0.31
HPSE Q9Y251 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27445430 0.97 ALOX5 (0.34) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27445449 0.96 PRKDC (0.34) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27445445 0.96 ALOX5 (0.35) ALOX5SIRT2SIRT1CHEK2LMNA
SCHEMBL27445342 0.94 KDM4E (0.33) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27445359 0.94 KDM4E (0.34) SIRT2SIRT1PRKDCHPSEKDM4E
SCHEMBL27445447 0.94 LMNA (0.32) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27445448 0.94 PRKDC (0.35) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27445343 0.93 KDM4E (0.33) SIRT2SIRT1PRKDCHPSEKDM4E
SCHEMBL27445381 0.93 PIM1 (0.32) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL27445404 0.93 PIM1 (0.32) ALOX5PIM1CSNK2A2CSNK2BPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-09 US disclosed
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2024-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030894-B2 Composition for organic optoelectronic device, organic optoelectronic device and display device OR10J3, OCIAD2, OCIAD1 ALOX5 581/4885PIM1 2606/4885CSNK2A2 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.