Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575400 | 0.81 | KDR (0.44) | KDRGCKBRAFMAPK14TNNI3K | |
| SCHEMBL27660846 | 0.81 | MAP4K4 (0.41) | KDRGCKBRAFMAPK14TNNI3K | |
| SCHEMBL12484107 | 0.77 | KMO (0.52) | KDRKMOGCKBRAFMAPK14 | |
| SCHEMBL29415420 | 0.76 | MEN1 (0.51) | KDRGCKBRAFMAPK14TNNI3K | |
| SCHEMBL6691249 | 0.76 | KDR (0.49) | KDRGCKBRAFMAPK14TNNI3K | |
| SCHEMBL27299880 | 0.74 | PDE4B (0.49) | KDM4EPOLBHTR2ASLC6A4KCNH2 | |
| SCHEMBL20522700 | 0.74 | KDR (0.46) | KDRKMOGCKBRAFMAPK14 | |
| SCHEMBL11196649 | 0.71 | HSP90AA1 (0.46) | KDRGCKBRAFMAPK14TNNI3K | |
| SCHEMBL27299885 | 0.71 | KDM4E (0.47) | KDM4EPOLBHTR2ASLC6A4KCNH2 | |
| SCHEMBL1895117 | 0.69 | MEN1 (0.50) | KDRGCKBRAFMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1303071-C | Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof | BAYER AG (DE) | 2007-03-07 | — | — | CN | disclosed |
| CN-1229329-C | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2005-11-30 | — | — | CN | disclosed |
| CN-1654459-A | Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof | BAYER CROPSCIENCE AG (DE) | 2005-08-17 | — | — | CN | disclosed |
| CN-1121393-C | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2003-09-17 | — | — | CN | disclosed |
| CN-1440962-A | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2003-09-10 | — | — | CN | disclosed |
| CN-1250442-A | Substituted aminosalicylamides having fungicidal action and intermediates for their preparation | BAYER AG (DE) | 2000-04-12 | — | — | CN | disclosed |