Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169685 | 0.81 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL1895117 | 0.81 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1MAPK14 | |
| SCHEMBL6691249 | 0.81 | KDR (0.49) | MEN1KMT2AL3MBTL1HTTMAPK14 | |
| SCHEMBL1136337 | 0.80 | SMN1; SMN2 (0.50) | L3MBTL1ALDH1A1HTTMAPK14BRAF | |
| SCHEMBL11196649 | 0.79 | HSP90AA1 (0.46) | MAPK14BRAFKDRTNNI3KMAPT | |
| SCHEMBL12261855 | 0.77 | KDR (0.39) | MEN1KMT2AMAPK14BRAFKDR | |
| SCHEMBL6329262 | 0.77 | CYP2D6 (0.55) | MEN1KMT2AKDM4EHSPB1L3MBTL1 | |
| SCHEMBL10033144 | 0.77 | RAB9A (0.55) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL27445864 | 0.76 | KDR (0.41) | KDM4EMAPK14BRAFKDRTNNI3K | |
| SCHEMBL18575400 | 0.76 | KDR (0.44) | MEN1KMT2AKDM4EHSPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073508-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073508-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | MEN1 1532/4885KMT2A 2721/4885KDM4E 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.