SCHEMBL27445868

SCHEMBL27445868

FC(F)(F)OSCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
PRMT1 Q99873 1/20 0.38
IDO1 P14902 3/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
CETP P11597 1/20 0.37
CES1 P23141 2/20 0.36
POLB P06746 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
MAOB P27338 1/20 0.36
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18531376 0.79 BCHE (0.45) CYP1A2CYP3A4IDO1CETPALDH1A1
SCHEMBL8580874 0.75 IDO1 (0.41) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL8450 0.74 IDO1 (0.44) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL27634197 0.73 IDO1 (0.40) CYP1A2CYP3A4CYP2D6PRMT1IDO1
Water SCHEMBL28337532 0.72 IDO1 (0.43) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL10666358 0.71 IDO1 (0.39) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL546541 0.70 CYP1A2 (0.42) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL2154643 0.70 CYP1A2 (0.52) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL7955699 0.70 IDO1 (0.41) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL14081414 0.70 IDO1 (0.46) CYP1A2CYP3A4CYP2D6PRMT1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1139103-A Process for synthesis of hydrocarbon compounds which are fluorinated on carbon of alkyl chain RHONE POULENC CHIMIE (FR) 1997-01-01 CN disclosed