SCHEMBL8450

SCHEMBL8450

c1ccc(CSOSCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
TSHR P16473 2/20 0.43
MAOB P27338 1/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CALM1 P0DP23 1/20 0.43
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
PRMT1 Q99873 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28337532 0.97 IDO1 (0.43) IDO1NOS3NOS1NOS2TSHR
Thiophene SCHEMBL27980591 0.87 IDO1 (0.36) IDO1NOS3NOS1NOS2TSHR
SCHEMBL8825504 0.85 IDO1 (0.48) IDO1TSHRCA12CA1CA2
Acetic Acid Methyl Ester SCHEMBL28504359 0.82 ALDH1A1 (0.48) POLBCYP2C19
Acetic Acid SCHEMBL28536489 0.82 ALDH1A1 (0.44) IDO1POLBCA12CA9CYP2C19
SCHEMBL19514655 0.80 CYP2C19 (0.44) IDO1NOS3NOS1NOS2TSHR
SCHEMBL14081414 0.79 IDO1 (0.46) IDO1NOS3NOS1NOS2TSHR
SCHEMBL8580874 0.79 IDO1 (0.41) IDO1NOS3NOS1NOS2TSHR
SCHEMBL7955699 0.79 IDO1 (0.41) IDO1NOS3NOS1NOS2TSHR
SCHEMBL546541 0.79 CYP1A2 (0.42) IDO1NOS3NOS1NOS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3152 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768791-B1 WEATHER-RESISTANT ADHESIVE WITH GOOD FLOWING CAPABILITY AND ADHESIVE TAPES BASED ON SAME TESA SE (DE) 2026-05-06 EP claimed
CN-115651017-B Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2025-05-27 CN claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
CN-115477600-B Preparation method of benzyl thioether compound 浙江理工大学 2023-12-19 CN claimed
CN-115197041-B Deuteration method for benzyl carbon-hydrogen bond 复旦大学 2023-12-01 CN claimed
CN-112585232-B Weather-resistant adhesive with good flowability and adhesive tape based on same 德莎欧洲股份公司 2023-02-21 CN claimed
CN-115651017-A Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2023-01-31 CN claimed
CN-115477600-A Preparation method of benzyl sulfide compound 浙江理工大学 2022-12-16 CN claimed
CN-115197041-A Deuterated method for benzylic carbon-hydrogen bond 复旦大学 2022-10-18 CN claimed
CN-111690346-B Reduced odor natural rubber-based adhesives 德莎欧洲股份公司 2022-09-06 CN claimed
US-6984428-B2 block copolymer, tackifier resins, antioxidants and sterically hindered benzyl thioether containing compounds, phenyl acrylate containing compound and lactones; redetachable by extensive stretching in the bond plane TESA AKTIENGESELLSCHAFT (DE) 2006-01-10 US claimed
EP-1341862-B1 PRESSURE-SENSITIVE ADHESIVE MASS AND THE USE THEREOF TESA AG (DE) 2005-06-22 EP claimed
US-20040110882-A1 block copolymer, tackifier resins, antioxidants and sterically hindered benzyl thioether containing compounds, phenyl acrylate containing compound and lactones; redetachable by extensive stretching in the bond plane TESA SE (DE) 2004-06-10 US claimed
US-20030113279-A1 Photoactivatable composition and uses thereof L'OREAL (FR) 2003-06-19 US claimed
US-6344537-B1 RUBBER COMPOSITION WITH TWO THIIRANES AND PROTECTED GROUP WITH CARBONYL THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-02-05 US claimed
CN-1192741-A Vinyl sulfoxide compound and synthetic method thereof LILLY CO ELI (US) 1998-09-09 CN claimed
CN-1150797-A Benzylsulfide derivative, process for its production and pesticide KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-05-28 CN claimed
US-5006534-A Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1991-04-09 US claimed
US-4786684-A SOLID PHASE SYNTHESIS THE MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) 1988-11-22 US claimed
WO-1988001173-A1 BENZYLTHIOETHER-LINKED SOLID SUPPORT-BOUND THIOL COMPOUNDS AND METHOD FOR PEPTIDE SYNTHESIS THE MOUNT SINAI SCHOOL OF MEDICINE (US) 1988-02-25 WO claimed