SCHEMBL8580874

SCHEMBL8580874

FOSCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAOB P27338 1/20 0.40
CALM1 P0DP23 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
PRMT1 Q99873 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8450 0.79 IDO1 (0.44) IDO1NOS3NOS1NOS2TSHR
Water SCHEMBL28337532 0.77 IDO1 (0.43) IDO1NOS3NOS1NOS2TSHR
SCHEMBL10666358 0.76 IDO1 (0.39) IDO1NOS3NOS1NOS2TSHR
SCHEMBL7955699 0.75 IDO1 (0.41) IDO1NOS3NOS1NOS2TSHR
SCHEMBL546541 0.75 CYP1A2 (0.42) IDO1NOS3NOS1NOS2TSHR
SCHEMBL14081414 0.75 IDO1 (0.46) IDO1NOS3NOS1NOS2TSHR
SCHEMBL28335148 0.75 IDO1 (0.48) IDO1NOS3NOS1NOS2TSHR
SCHEMBL27445868 0.75 CYP1A2 (0.38) IDO1NOS3NOS1NOS2TSHR
SCHEMBL27634197 0.73 IDO1 (0.40) IDO1NOS3NOS1NOS2TSHR
SCHEMBL4194780 0.73 IDO1 (0.40) IDO1NOS3NOS1NOS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710251-A ION EXCHANGING WITH ANIONS AND CATIONS AND APPLYING HYDROXYAPATITE CHROMATOGRAPHY SCHERING CORPORATION (US) 1998-01-20 US disclosed
EP-0688335-A1 PURIFICATION OF HUMAN INTERLEUKIN-10 SCHERING CORPORATION (US) 1995-12-27 EP disclosed
WO-1994020525-A1 PURIFICATION OF HUMAN INTERLEUKIN-10 SCHERING CORPORATION (US) 1994-09-15 WO disclosed