Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGAV | P06756 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 11/20 | 0.39 |
| ▸ | THRA | P10827 | 9/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | PCNA | P12004 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27446346 | 0.93 | ITGB3 (0.44) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL27446226 | 0.91 | ITGB3 (0.43) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL27446221 | 0.88 | ITGB3 (0.48) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21100868 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21101049 | 0.85 | ITGB3 (0.54) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL23709969 | 0.77 | ITGB3 (0.54) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21100863 | 0.76 | ITGB3 (0.45) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL12764506 | 0.71 | THRB (0.57) | ITGB3ITGAVTHRBTHRAPPARG | |
| SCHEMBL21064809 | 0.71 | ITGB3 (0.77) | ITGB3ITGAV | |
| SCHEMBL23709876 | 0.70 | THRB (0.62) | ITGB3ITGAVTHRBTHRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773540-B1 | COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS | NANOPHARMACEUTICALS LLC (US) | 2024-07-03 | — | — | EP | disclosed |