Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.80 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.61 |
| ▸ | ITGAL | P20701 | 8/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294032 | 0.92 | UBASH3B (0.85) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| SCHEMBL9293799 | 0.90 | UBASH3B (0.82) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL23346201 | 0.89 | UBASH3B (1.00) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL21623658 | 0.89 | UBASH3B (1.00) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| SCHEMBL9293895 | 0.89 | UBASH3B (0.80) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL29560992 | 0.89 | UBASH3B (1.00) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL221527 | 0.89 | UBASH3B (1.00) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL5794018 | 0.89 | UBASH3B (1.00) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| SCHEMBL10840354 | 0.89 | UBASH3B (0.80) | UBASH3BITGB2ICAM1ITGALERAP2 | |
| Rebamipide SCHEMBL9114879 | 0.88 | UBASH3B (0.98) | UBASH3BITGB2ICAM1ITGALERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073418-C | Interleukin-8 production inhibitor | 大塚制药株式会社 | 2001-10-24 | — | — | CN | disclosed |