Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663252 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL7503276 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL9056119 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL7442607 | 0.83 | DRD2 (0.51) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL23458882 | 0.80 | DRD2 (0.49) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL29919242 | 0.80 | DRD2 (0.49) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL6238686 | 0.78 | DRD2 (0.50) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL31017907 | 0.77 | LOXL2 (0.73) | LOXL2ITK | |
| Bromide SCHEMBL7386050 | 0.73 | DRD2 (0.52) | DRD2DRD4DRD3IMPDH2IMPDH1 | |
| SCHEMBL30920844 | 0.73 | LOXL2 (0.58) | LOXL2ITKNOS1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112830-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |