SCHEMBL2744786

SCHEMBL2744786

C1=C(c2cscc2C2=CCCC2)CCC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 5/20 0.34
KDR P35968 2/20 0.34
PSMB1 P20618 1/20 0.34
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
TYMP P19971 1/20 0.32
GRM2 Q14416 1/20 0.32
PTGS2 P35354 1/20 0.32
F2RL1 P55085 1/20 0.31
ACMSD Q8TDX5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744834 0.93 PSMB5 (0.40) PSMB5KDRPSMB1CCNE1CDK2
SCHEMBL27173426 0.79 PSMB5 (0.45) PSMB5KDRPSMB1CCNE1CDK2
SCHEMBL7209639 0.79 PSMB5 (0.38) PSMB5KDRPSMB1CCNE1CDK2
SCHEMBL15048839 0.74 TYMP (0.40) PSMB5KDRCCNE1CDK2TYMP
SCHEMBL604266 0.74 TYMP (0.40) PSMB5KDRCCNE1CDK2TYMP
SCHEMBL7203713 0.72 ACMSD (0.37) PSMB5PSMB1CCNE1CDK2GRM2
SCHEMBL28758944 0.72 PTGS2 (0.51) PSMB5KDRCCNE1CDK2TYMP
SCHEMBL2744580 0.72 PTGER1 (0.33) PSMB5PSMB1GRM2
SCHEMBL7991306 0.70 CCNE1 (0.33) PSMB5KDRPSMB1CCNE1CDK2
SCHEMBL1109730 0.69 TYMP (0.41) PSMB5PSMB1CCNE1CDK2TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US claimed
WO-2005014693-A1 METHOD OF CROSSLINKING INTRINSICALLY CONDUCTIVE POLYMERS OR INTRINSICALLY CONDUCTIVE POLYMER PRECURSORS AND THE ARTICLES OBTAINED THEREFROM UNIVERSITY OF CONNECTICUT (US) 2005-02-17 WO claimed
US-20040242792-A1 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom CONNECTICUT, THE UNIVERSITY OF 2004-12-02 US claimed
US-20120196078-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF SOTZING GREGORY A (US) 2012-08-02 US disclosed
US-8178629-B2 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT (US) 2012-05-15 US disclosed
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US disclosed
US-20070089845-A1 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT 2007-04-26 US disclosed
WO-2006084088-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2006-08-10 WO disclosed
US-20040242792-A1 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom CONNECTICUT, THE UNIVERSITY OF 2004-12-02 US disclosed
EP-0885251-B1 SUBSTITUTED POLYTHIOPHENES, PROCESSES FOR THEIR PREPARATION AND THEIR USE BASF AG (DE) 2001-08-16 EP disclosed
US-6242561-B1 USED AS SEMICONDUCTORS; ELECTROCHROMIC AND ANTISTATIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed
EP-0885251-A1 SUBSTITUTED POLYTHIOPHENES, PROCESSES FOR THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1998-12-23 EP disclosed
WO-1997032914-A1 SUBSTITUTED POLYTHIOPHENES, PROCESSES FOR THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1997-09-12 WO disclosed