Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311500 | 0.88 | F10 (0.38) | ESR2HRH3CYP3A4CYP2C9F10 | |
| SCHEMBL27408738 | 0.88 | F10 (0.38) | ESR2HRH3CYP3A4CYP2C9F10 | |
| SCHEMBL27519051 | 0.88 | F10 (0.38) | ESR2HRH3CYP3A4CYP2C9F10 | |
| SCHEMBL27310569 | 0.86 | PDE4A (0.38) | ESR2HRH3CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27310571 | 0.86 | PDE4A (0.38) | ESR2HRH3CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27325072 | 0.83 | LMNA (0.38) | ESR2HRH3 | |
| SCHEMBL27319008 | 0.80 | PDE4A (0.40) | ESR2CYP3A4CYP2C9CYP2C19PDE4A | |
| SCHEMBL27638664 | 0.78 | AKR1C3 (0.30) | — | |
| SCHEMBL27600870 | 0.78 | AKR1C3 (0.30) | — | |
| SCHEMBL27524574 | 0.77 | SIRT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051308-C | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 2000-04-12 | — | — | CN | disclosed |
| CN-1109054-A | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-27 | — | — | CN | disclosed |