SCHEMBL27449307

SCHEMBL27449307

Cc1cc(C)c2c(c1)C([Zr])C(c1ccccc1)=C2

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
PSMB5 P28074 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8079657 0.79 LMNA (0.33) LMNAPSMB5SMN1; SMN2MCOLN3L3MBTL1
SCHEMBL8079661 0.77 LMNA (0.34) LMNAPSMB5SMN1; SMN2MCOLN3
SCHEMBL27508402 0.73 NPC1 (0.30) SMN1; SMN2RAB9A
SCHEMBL27468525 0.73 LMNA (0.31) LMNATSHRALOX12ACHE
SCHEMBL27737014 0.72 EDNRB (0.36) LMNASMN1; SMN2MCOLN3L3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL5695378 0.72 UGT2B17 (0.31)
SCHEMBL27757805 0.71 METAP2 (0.36) LMNAPSMB5SMN1; SMN2MCOLN3L3MBTL1
SCHEMBL28024193 0.70 METAP2 (0.35) LMNAPSMB5SMN1; SMN2MCOLN3TSHR
Hydrochloric Acid SCHEMBL28035005 0.69 METAP2 (0.34) PSMB5
SCHEMBL8674878 0.68 TACR1 (0.35) LMNATSHRALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1147822-A Reactor blend polypropylene, process for the preparation thereof and process for preparing metallocene ligands MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-16 CN disclosed