Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27421867 | 0.84 | CREBBP (0.36) | ALDH1A1BRD4CREBBPMAPTMEN1 | |
| SCHEMBL23581199 | 0.75 | PDK2 (0.40) | ALDH1A1BRD4CREBBPMAPTMEN1 | |
| SCHEMBL26107258 | 0.70 | KDM1A (0.44) | ALDH1A1BRD4CREBBPMEN1GAA | |
| SCHEMBL28453797 | 0.69 | KDM1A (0.36) | ALDH1A1BRD4CREBBPMEN1GAA | |
| SCHEMBL27460828 | 0.68 | KDM4E (0.34) | ALDH1A1MAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL29076752 | 0.68 | KDM1A (0.38) | ALDH1A1MEN1GAAKMT2ATSHR | |
| SCHEMBL28496380 | 0.67 | PDE7A (0.41) | ALDH1A1SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL27568811 | 0.65 | CREBBP (0.39) | ALDH1A1BRD4CREBBPMAPTSMN1; SMN2 | |
| SCHEMBL28467068 | 0.64 | CYP2D6 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX15 | |
| SCHEMBL28998851 | 0.64 | BACE1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117727-A | Indolin-2-one derivative | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1996-02-28 | — | — | CN | disclosed |