Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496380 | 0.95 | PDE7A (0.41) | KDM1AALDH1A1GAAMEN1POLB | |
| SCHEMBL28904764 | 0.86 | KDM1A (0.40) | KDM1AALDH1A1OPRM1OPRK1OPRL1 | |
| SCHEMBL28453797 | 0.85 | KDM1A (0.36) | KDM1AALDH1A1GAAMEN1POLB | |
| SCHEMBL28496477 | 0.82 | KDM1A (0.32) | KDM1A | |
| SCHEMBL28998851 | 0.81 | BACE1 (0.43) | KDM1ASLC6A2SLC6A4BACE1 | |
| SCHEMBL28933778 | 0.75 | POLB (0.37) | KDM1AGAAPOLBLMNA | |
| SCHEMBL28467068 | 0.75 | CYP2D6 (0.33) | KDM1AALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL23581199 | 0.74 | PDK2 (0.40) | ALDH1A1GAAMEN1POLBKMT2A | |
| SCHEMBL28692448 | 0.71 | LMNA (0.36) | KDM1AALDH1A1GAAPOLBLMNA | |
| SCHEMBL28413703 | 0.67 | KDM1A (0.38) | KDM1AOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |