SCHEMBL2744952

SCHEMBL2744952

Brc1ccc(-c2nnc(-c3ccccn3)n2-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
DCTPP1 Q9H773 1/20 0.52
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 1/20 0.47
AVPR1A P37288 1/20 0.46
TERT O14746 1/20 0.46
TSHR P16473 3/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
OPRK1 P41145 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 3/20 0.43
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744404 0.92 DCTPP1 (0.50) RXFP1MEN1KMT2ADCTPP1LMNA
SCHEMBL18069678 0.87 AVPR1A (0.51) MEN1KMT2ADCTPP1SMN1; SMN2HPGD
SCHEMBL18682230 0.86 RXFP1 (0.75) RXFP1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL515312 0.84 RXFP1 (0.73) RXFP1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL713513 0.82 SMN1; SMN2 (0.47) RXFP1MEN1KMT2ADCTPP1LMNA
SCHEMBL2745010 0.82 KDM4E (0.49) RXFP1MEN1KMT2ADCTPP1SMN1; SMN2
SCHEMBL10035318 0.81 AVPR1A (0.51) RXFP1MEN1KMT2ADCTPP1LMNA
SCHEMBL13492089 0.81 RXFP1 (0.65) RXFP1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL14280138 0.81 RXFP1 (0.44) RXFP1MEN1KMT2ADCTPP1LMNA
SCHEMBL28079997 0.80 HSD17B10 (0.52) SMN1; SMN2TSHRNPC1TP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10790451-B2 Triazole derivative, and light-emitting element, light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-09-29 US disclosed
CN-110724124-A Triazole derivatives 株式会社半导体能源研究所 2020-01-24 CN disclosed
US-20160268515-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2016-09-15 US disclosed
US-20160268515-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2016-09-15 US disclosed
US-20160268515-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2016-09-15 US disclosed
US-9397299-B2 Triazole derivative, and light-emitting element, light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-19 US disclosed
US-9397299-B2 Triazole derivative, and light-emitting element, light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-19 US disclosed
US-9397299-B2 Triazole derivative, and light-emitting element, light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-19 US disclosed
CN-101679383-B Triazole derivative, and light-emitting element, light-emitting device, and electronic device using triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO.,LTD. (JP) 2014-10-29 CN disclosed
US-20140042420-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-13 US disclosed
US-20120199818-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-09 US disclosed
US-8178217-B2 4-(4-bromophenyl)-3,5-diphenyl-4H-1,2,4-triazole; high triplet excitation energy; high luminous efficiency, low power consumption SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-8178217-B2 4-(4-bromophenyl)-3,5-diphenyl-4H-1,2,4-triazole; high triplet excitation energy; high luminous efficiency, low power consumption SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-8178217-B2 4-(4-bromophenyl)-3,5-diphenyl-4H-1,2,4-triazole; high triplet excitation energy; high luminous efficiency, low power consumption SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
CN-101679383-A Triazole derivative, and light-emitting element, light-emitting device, and electronic device using triazole derivative SEMICONDUCTOR ENERGY LAB 2010-03-24 CN disclosed
WO-2008143019-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-11-27 WO disclosed
WO-2008143019-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-11-27 WO disclosed
US-20080286607-A1 Triazole derivative, and light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-11-20 US disclosed
US-20080286607-A1 Triazole derivative, and light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-11-20 US disclosed
US-20080286607-A1 Triazole derivative, and light-emitting device, and electronic device with the use of triazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199818-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE TYR, TH, YEATS4 RXFP1 4405/4885MEN1 3934/4885KMT2A 1412/4885
US-20160268515-A1 TRIAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE WITH THE USE OF TRIAZOLE DERIVATIVE TYR, TH, YEATS4 RXFP1 4405/4885MEN1 3934/4885KMT2A 1412/4885
US-10790451-B2 Triazole derivative, and light-emitting element, light-emitting device, and electronic device with the use of triazole derivative TYR, TH, YEATS4 RXFP1 4405/4885MEN1 3934/4885KMT2A 1412/4885
US-20080286607-A1 Triazole derivative, and light-emitting device, and electronic device with the use of triazole derivative TYR, TH, CYP3A4 RXFP1 4330/4885MEN1 3872/4885KMT2A 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.