Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757830 | 0.73 | LMNA (0.39) | LMNAGAAHTR3AHTR2APOLB | |
| SCHEMBL28269446 | 0.64 | POLB (0.41) | LMNAPOLB | |
| SCHEMBL1234460 | 0.63 | — | — | |
| SCHEMBL1082344 | 0.63 | — | — | |
| SCHEMBL5863813 | 0.62 | OPRM1 (0.42) | HTR2A | |
| SCHEMBL14833466 | 0.62 | HTR2A (0.36) | HTR3AHTR2A | |
| Methylamine SCHEMBL27471205 | 0.60 | OPRM1 (0.40) | HTR2A | |
| SCHEMBL28287844 | 0.60 | OPRM1 (0.37) | LMNAGAAHTR2ACYP1A2 | |
| SCHEMBL9749001 | 0.60 | NPFFR1 (0.46) | HTR2ACYP1A2CYP2C9POLB | |
| SCHEMBL4434037 | 0.60 | HTR2A (0.33) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1290700-A | Phenyl piperazine derivatives | EISAI LTD (JP) | 2001-04-11 | — | — | CN | disclosed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | disclosed |