Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451347 | 0.88 | RAB9A (0.64) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27451505 | 0.85 | NPC1 (0.59) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL31050189 | 0.85 | NPC1 (0.59) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL31050188 | 0.85 | NPC1 (0.59) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27451353 | 0.76 | NPC1 (0.64) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL31050186 | 0.72 | RAB9A (0.48) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27451289 | 0.72 | MAPT (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27451116 | 0.72 | RAB9A (0.77) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27452497 | 0.72 | MEN1 (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27451351 | 0.71 | RAB9A (0.68) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |