Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079971 | 1.00 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL27451922 | 1.00 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL15600964 | 0.85 | KDM4E (0.41) | KDM4EBTKEGFRALDH1A1ERBB2 | |
| SCHEMBL14079974 | 0.85 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL20927103 | 0.85 | HTT (0.49) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL24371639 | 0.84 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL23336391 | 0.84 | KDM4E (0.43) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL16665574 | 0.83 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL15600841 | 0.83 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL15601151 | 0.83 | CHRNB2 (0.42) | MEN1KMT2ABTKEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |