Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452151 | 0.86 | MEN1 (0.61) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL27452951 | 0.83 | MEN1 (0.60) | HTTPOLBMEN1KMT2AMAPT | |
| SCHEMBL27452291 | 0.83 | LMNA (0.60) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL27453206 | 0.82 | MEN1 (0.57) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL27451278 | 0.80 | MEN1 (0.62) | HTTPOLBMEN1KMT2AMAPT | |
| SCHEMBL27452429 | 0.79 | LMNA (0.59) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL27452283 | 0.77 | HTT (0.53) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL6034952 | 0.77 | LMNA (1.00) | HTTPOLBMEN1KMT2ALMNA | |
| SCHEMBL27453115 | 0.77 | LMNA (0.56) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL27452497 | 0.75 | MEN1 (0.61) | HTTPOLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |