Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452284 | 0.87 | NAMPT (0.69) | LMNAMAPTNAMPTPOLBMEN1 | |
| SCHEMBL27452211 | 0.83 | HTT (0.64) | LMNAMAPTNAMPTPOLBMEN1 | |
| SCHEMBL27452495 | 0.82 | NAMPT (0.54) | LMNAMAPTNAMPTPOLBMEN1 | |
| SCHEMBL27451212 | 0.81 | NAMPT (0.71) | MAPTNAMPTPOLBMEN1KMT2A | |
| SCHEMBL27452347 | 0.79 | NAMPT (0.51) | LMNAMAPTNAMPTPOLBMEN1 | |
| SCHEMBL27452429 | 0.77 | LMNA (0.59) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL6034952 | 0.76 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL27453115 | 0.75 | LMNA (0.56) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL27452286 | 0.75 | NAMPT (0.55) | MAPTNAMPTPOLBMEN1KMT2A | |
| SCHEMBL27452151 | 0.71 | MEN1 (0.61) | LMNAMAPTNAMPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |