Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782362 | 0.80 | DRD2 (0.64) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL6227275 | 0.79 | MAPT (0.73) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11887784 | 0.79 | POLB (0.84) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8234055 | 0.78 | HDAC1 (0.79) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL10695859 | 0.78 | MAPT (0.75) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3239389 | 0.78 | POLB (0.82) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5070926 | 0.77 | POLB (0.76) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19287153 | 0.77 | POLB (0.71) | ADORA2AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL20369717 | 0.77 | MAPT (0.77) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19771114 | 0.76 | POLB (0.74) | ADORA2AHDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |