Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13676389 | 0.85 | L3MBTL1 (0.41) | L3MBTL1TGFBR1DYRK1AKEAP1GRM2 | |
| SCHEMBL24231953 | 0.82 | TGFBR1 (0.43) | L3MBTL1TGFBR1DYRK1AKEAP1MEN1 | |
| SCHEMBL11985799 | 0.82 | L3MBTL1 (0.44) | L3MBTL1TGFBR1DYRK1AKEAP1RORC | |
| SCHEMBL16581970 | 0.77 | L3MBTL1 (0.41) | L3MBTL1TGFBR1DYRK1AKEAP1RORC | |
| SCHEMBL3323254 | 0.77 | L3MBTL1 (0.41) | L3MBTL1TGFBR1DYRK1AKEAP1RORC | |
| SCHEMBL407441 | 0.77 | L3MBTL1 (0.49) | L3MBTL1TGFBR1DYRK1AKEAP1RORC | |
| SCHEMBL22745442 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TGFBR1DYRK1AKEAP1MEN1 | |
| SCHEMBL24087290 | 0.77 | TGFBR1 (0.46) | TGFBR1DYRK1AKEAP1GRM2MEN1 | |
| SCHEMBL24463401 | 0.77 | TGFBR1 (0.38) | TGFBR1DYRK1AKEAP1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL31647268 | 0.76 | L3MBTL1 (0.47) | L3MBTL1TGFBR1DYRK1AKEAP1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976189-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2024-07-03 | — | — | EP | disclosed |