Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452582 | 1.00 | POLB (0.44) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27452869 | 1.00 | POLB (0.44) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27452650 | 0.94 | POLB (0.45) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27452581 | 0.94 | POLB (0.45) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27453121 | 0.91 | ALDH1A1 (0.47) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27453022 | 0.91 | ALDH1A1 (0.47) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27453122 | 0.91 | ALDH1A1 (0.47) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27453209 | 0.83 | POLB (0.47) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27452788 | 0.81 | SMN1; SMN2 (0.44) | POLBSMN1; SMN2LMNARECQLL3MBTL1 | |
| SCHEMBL27452834 | 0.81 | SMN1; SMN2 (0.44) | POLBSMN1; SMN2LMNARECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |