Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453122 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27453121 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452582 | 0.91 | POLB (0.44) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452869 | 0.91 | POLB (0.44) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452886 | 0.91 | POLB (0.44) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452650 | 0.89 | POLB (0.45) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452581 | 0.89 | POLB (0.45) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452584 | 0.82 | POLB (0.42) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA | |
| SCHEMBL27452949 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL27451894 | 0.79 | LMNA (0.48) | ALDH1A1HPGDMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |