Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451638 | 0.85 | MAPT (0.64) | MAPTTP53RAB9AMEN1KMT2A | |
| SCHEMBL27452351 | 0.84 | MAPT (0.77) | MAPTTP53LMNARAB9AMEN1 | |
| SCHEMBL27452354 | 0.82 | MAPT (0.60) | MAPTRXFP1TP53LMNARAB9A | |
| SCHEMBL27451289 | 0.82 | MAPT (0.53) | MAPTRXFP1TP53LMNARAB9A | |
| SCHEMBL27452355 | 0.82 | MAPT (0.63) | MAPTTP53RAB9AMEN1KMT2A | |
| SCHEMBL27452210 | 0.81 | MAPT (0.53) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL27452866 | 0.80 | TP53 (0.60) | MAPTRXFP1TP53LMNARAB9A | |
| SCHEMBL27452712 | 0.80 | MAPT (0.59) | MAPTTP53LMNARAB9AMEN1 | |
| SCHEMBL27451199 | 0.78 | RAB9A (0.67) | MAPTRXFP1TP53RAB9AMEN1 | |
| SCHEMBL13903823 | 0.78 | MAPT (0.70) | MAPTRXFP1TP53LMNAAGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |