Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451289 | 0.89 | MAPT (0.53) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27451638 | 0.85 | MAPT (0.64) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452355 | 0.84 | MAPT (0.63) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452351 | 0.82 | MAPT (0.77) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452146 | 0.82 | NPC1 (0.55) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452862 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452888 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452354 | 0.81 | MAPT (0.60) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27452724 | 0.80 | MAPT (0.67) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL27451199 | 0.78 | RAB9A (0.67) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |