Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136140 | 0.81 | HTR6 (0.48) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL8529475 | 0.77 | HTR6 (0.39) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7135317 | 0.77 | HTR6 (0.53) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7192584 | 0.75 | HTR6 (0.62) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL8529471 | 0.74 | HTR6 (0.39) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7136141 | 0.72 | HTR6 (0.48) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL27453088 | 0.71 | HTR6 (0.47) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7143701 | 0.71 | HTR6 (0.47) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7140761 | 0.71 | HTR6 (0.67) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL8529467 | 0.70 | HTR6 (0.40) | HTR6LMNAMPOCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148356-C | Benzosulfone derivatives | - | 2004-05-05 | — | — | CN | claimed |
| CN-1231287-A | Benzosulfone derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-13 | — | — | CN | claimed |
| CN-1148356-C | Benzosulfone derivatives | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1231287-A | Benzosulfone derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-13 | — | — | CN | disclosed |