Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136141 | 0.80 | HTR6 (0.48) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL8529471 | 0.78 | HTR6 (0.39) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL27453090 | 0.77 | HTR6 (0.48) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7136140 | 0.77 | HTR6 (0.48) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7135317 | 0.76 | HTR6 (0.53) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL8529467 | 0.72 | HTR6 (0.40) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7143701 | 0.71 | HTR6 (0.47) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL27453089 | 0.70 | HTR6 (0.46) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL7192584 | 0.67 | HTR6 (0.62) | HTR6LMNAMPOCYP3A4CYP2C9 | |
| SCHEMBL27453088 | 0.66 | HTR6 (0.47) | HTR6LMNAMPOCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930302-A2 | Benzosulfone derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 1999-07-21 | — | — | EP | claimed |