SCHEMBL27454841

SCHEMBL27454841

Cc1cc(-c2ccccc2)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA9 Q16790 4/20 0.45
MCL1 Q07820 1/20 0.43
ACMSD Q8TDX5 1/20 0.43
ENPP3 O14638 1/20 0.43
ENPP1 P22413 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
MAPK1 P28482 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545233 0.89 ENPP3 (0.47) CA12CA1CA2CA9MCL1
SCHEMBL838870 0.89 ENPP3 (0.47) CA12CA1CA2CA9MCL1
SCHEMBL17932450 0.88 MAPT (0.47) MCL1ACMSDENPP3ENPP1ALDH1A1
SCHEMBL17949913 0.88 ENPP3 (0.47) MCL1ACMSDENPP3ENPP1ALDH1A1
SCHEMBL21120704 0.87 ENPP3 (0.47) CA12CA1CA2CA9MCL1
SCHEMBL15999941 0.87 ENPP3 (0.44) CA12CA1CA2CA9MCL1
Phosphine SCHEMBL28240948 0.87 ENPP3 (0.46) CA12CA1CA2CA9MCL1
SCHEMBL17932460 0.86 MEN1 (0.48) CA12CA1CA2CA9ENPP3
SCHEMBL17949947 0.85 ENPP3 (0.45) ENPP3ENPP1ALDH1A1KDM4EMAPT
SCHEMBL19998845 0.84 CA12 (0.46) CA12CA1CA2CA9MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862360-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed