SCHEMBL838870

SCHEMBL838870

Cc1cc(C)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.47
ENPP1 P22413 1/20 0.47
BRD9 Q9H8M2 1/20 0.47
BRD7 Q9NPI1 1/20 0.47
CYP2A6 P11509 3/20 0.47
CYP1A2 P05177 3/20 0.47
ALDH1A1 P00352 2/20 0.46
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
MCL1 Q07820 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA9 Q16790 4/20 0.43
CHRNA1 P02708 1/20 0.43
CHRNG P07510 1/20 0.43
CHRNB1 P11230 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545233 1.00 ENPP3 (0.47) ENPP3ENPP1BRD9BRD7CYP2A6
Phosphine SCHEMBL28240948 0.98 ENPP3 (0.46) ENPP3ENPP1BRD9BRD7CYP2A6
SCHEMBL27454841 0.89 CA12 (0.45) ENPP3ENPP1CYP2A6CYP1A2ALDH1A1
SCHEMBL25788028 0.87 ENPP3 (0.42) ENPP3ENPP1BRD9BRD7CYP2A6
SCHEMBL3357709 0.87 ALDH1A1 (0.47) ENPP3ENPP1CYP2A6CYP1A2ALDH1A1
SCHEMBL15856458 0.87 ENPP3 (0.42) ENPP3ENPP1BRD9BRD7CYP2A6
SCHEMBL22515944 0.87 ENPP3 (0.42) ENPP3ENPP1BRD9BRD7CYP2A6
SCHEMBL4323024 0.86 ENPP1 (0.48) ENPP3ENPP1CYP2A6CYP1A2ALDH1A1
SCHEMBL26214138 0.85 DHFR (0.45) ENPP3ENPP1BRD9BRD7CYP2A6
SCHEMBL29866205 0.84 CA12 (0.50) ENPP3ENPP1CYP2A6CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060932-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2026-03-05 US disclosed
US-20240238207-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2024-07-18 US disclosed
US-11911512-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2024-02-27 US disclosed
US-20230301921-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA L.P. 2023-09-28 US disclosed
CN-104873455-B Coated Tamper Resistant Controlled Release Dosage Forms 普渡制药公司 2023-09-12 CN disclosed
US-11590082-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2023-02-28 US disclosed
US-20210251907-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA L.P. 2021-08-19 US disclosed
US-10966932-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2021-04-06 US disclosed
US-20200121608-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2020-04-23 US disclosed
US-20190022086-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS PURDUE PHARMA LP (US) 2019-01-24 US disclosed
EP-1337244-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS Euroceltique S.A. (LU) 2003-08-27 EP disclosed
CN-1407884-A Controlled release hydrocodone formulations EURO CELTIQUE SA (LU) 2003-04-02 CN disclosed
US-20020192277-A1 Controlled release hydrocodone formulations PURDUE PHARMA L.P. 2002-12-19 US disclosed
EP-1227798-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS Euro-Celtique S.A. (LU) 2002-08-07 EP disclosed
WO-2002036099-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS EURO-CELTIQUE S.A. (LU) 2002-05-10 WO disclosed
WO-2000018378-A9 SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS EURO CELTIQUE SA (LU) 2001-07-19 WO disclosed
WO-2001032148-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS EURO-CELTIQUE, S.A. (LU) 2001-05-10 WO disclosed
WO-2000018378-A1 SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS EURO-CELTIQUE, S.A. (LU) 2000-04-06 WO disclosed
US-5668121-A Glutamate (NMDA) receptor antagonists WARNER-LAMBERT COMPANY (US) 1997-09-16 US disclosed
US-5489717-A Glutamate (NMDA) receptor antagonists WARNER-LAMBERT COMPANY 1996-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060932-A1 Encased Tamper Resistant Controlled Release Dosage Forms OGFR, OPRM1, OPRK1 ENPP3 3354/4885ENPP1 3594/4885BRD9 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.