Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | SORD | Q00796 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954035 | 1.00 | HRH3 (0.66) | HRH3HRH4GSK3AGSK3BROCK1 | |
| SCHEMBL18072491 | 0.81 | HRH3 (0.62) | HRH3HRH4ROCK1OGAROCK2 | |
| SCHEMBL14880196 | 0.80 | HRH3 (0.71) | HRH3HRH4ROCK1OGANUDT1 | |
| SCHEMBL17626748 | 0.80 | HRH3 (0.71) | HRH3HRH4ROCK1OGAMAP3K14 | |
| SCHEMBL30954009 | 0.80 | TRPV1 (0.47) | HRH3HRH4OGASORD | |
| SCHEMBL26618088 | 0.80 | TRPV1 (0.47) | HRH3HRH4OGASORD | |
| SCHEMBL30693986 | 0.80 | HRH3 (0.43) | HRH3HRH4ROCK2SORD | |
| SCHEMBL13018701 | 0.80 | HRH3 (0.65) | HRH3HRH4ROCK1OGAROCK2 | |
| SCHEMBL2166795 | 0.80 | HRH3 (1.00) | HRH3HRH4ROCK1OGAROCK2 | |
| Bromide SCHEMBL20445910 | 0.79 | HRH3 (0.69) | HRH3HRH4ROCK1OGANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |