SCHEMBL30693986

SCHEMBL30693986

FC1(F)CCN(c2ccnc(Br)n2)CC1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 5/20 0.43
▸ SORD Q00796 2/20 0.40
▸ TRPV3 Q8NET8 1/20 0.40
▸ PDE10A Q9Y233 2/20 0.39
▸ HRH4 Q9H3N8 4/20 0.38
▸ ROCK2 O75116 1/20 0.36
▸ CNR2 P34972 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PTGER4 P35408 1/20 0.35
▸ ACACB O00763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954009 0.80 TRPV1 (0.47) HRH3SORDPDE10AHRH4CNR2
SCHEMBL27454974 0.80 HRH3 (0.66) HRH3SORDHRH4ROCK2
SCHEMBL30954035 0.80 HRH3 (0.66) HRH3SORDHRH4ROCK2
SCHEMBL26618088 0.80 TRPV1 (0.47) HRH3SORDPDE10AHRH4CNR2
SCHEMBL21812367 0.77 ADRB1 (0.39) HRH4CNR2ACACB
SCHEMBL31346241 0.77 ADRB1 (0.39) HRH4CNR2ACACB
SCHEMBL21914804 0.76 PIK3CA (0.50) SORDALDH1A1GAASMN1; SMN2
SCHEMBL29790016 0.76 PIK3CA (0.50) SORDALDH1A1GAASMN1; SMN2
SCHEMBL27457780 0.75 PTGER4 (0.45) HRH3SORDTRPV3HRH4ROCK2
SCHEMBL17619976 0.75 GRIN2D (0.50) TRPV3PDE10ACNR2ALDH1A1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522593-B2 Azacycloalkyl carbonyl cyclic amine compound ALIVEXIS, INC. (JP) 2026-01-13 — — US disclosed
US-20250163041-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND ALIVEXIS, INC. (JP) 2025-05-22 — — US disclosed
EP-4538264-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND Alivexis, Inc. (JP) 2025-04-16 — — EP disclosed
CN-119317620-A Azacycloalkyl carbonyl cyclic amine compounds 亚力维克希斯股份有限公司 2025-01-14 — — CN disclosed
WO-2023243601-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND モジュラス株式会社 2023-12-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163041-A1 AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND NCF1, ELANE, MPO HRH3 509/4885SORD 2200/4885TRPV3 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback