Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.42 |
| ▸ | ATP4B | P51164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.40 |
| ▸ | HRH2 | P25021 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813815 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL2744621 | 0.83 | SMN1; SMN2 (0.50) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL3842184 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL727235 | 0.81 | PRMT1 (0.53) | HRH3 | |
| SCHEMBL2745522 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL729007 | 0.79 | ATP4A (0.38) | ALDH1A1ATP4AATP4BHDAC1HDAC2 | |
| SCHEMBL2745723 | 0.77 | HRH3 (0.50) | ALDH1A1HPGDKDM4EHTTHRH3 | |
| SCHEMBL2814210 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL2813043 | 0.74 | MEN1 (0.46) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL2813546 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781629-B1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARM CO LTD (KR) | 2015-07-29 | — | — | EP | disclosed |
| US-8178688-B2 | Benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2012-05-15 | — | — | US | disclosed |
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | ALDH1A1 1751/4885HPGD 1617/4885KDM4E 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.