Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.65 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095287 | 1.00 | GNAI3 (0.65) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL26748741 | 0.93 | NPC1 (0.56) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL23795580 | 0.91 | GNAI3 (0.57) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL23136096 | 0.86 | NPC1 (0.47) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL21471053 | 0.83 | NPC1 (0.46) | GNAI3GNAI1GNAO1L3MBTL1NPC1 | |
| SCHEMBL26568580 | 0.83 | NPC1 (0.46) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL14879738 | 0.81 | NPC1 (0.76) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL3365303 | 0.81 | NPC1 (0.76) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL22147028 | 0.81 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL8642325 | 0.81 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145315-A1 | TARGETED PROTEIN DEGRADERS OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) | NORTHWESTERN UNIVERSITY (US) | 2024-07-04 | — | — | WO | disclosed |