Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246469 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9750495 | 0.80 | CYP2D6 (0.51) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9152731 | 0.80 | CYP2D6 (0.51) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27536300 | 0.79 | SOAT1 (0.51) | MAPTMEN1KMT2AKDM4EFFAR4 | |
| SCHEMBL10585164 | 0.79 | CYP2D6 (0.53) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13123849 | 0.79 | RAB9A (0.60) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8748861 | 0.79 | RAB9A (0.60) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8748694 | 0.79 | RAB9A (0.60) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8748904 | 0.79 | RAB9A (0.60) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6951827 | 0.77 | CYP3A4 (0.47) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143638-A | Derivatives of alkoxyalkoxy-substituted nitrogen containing heterocyclic compounds | ROLIC AG (CH) | 1997-02-26 | — | — | CN | disclosed |