Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058835 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL2006753 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL11974276 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL29439910 | 0.76 | ALDH1A1 (0.76) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL5329303 | 0.76 | ALDH1A1 (0.76) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL9056926 | 0.76 | LMNA (0.58) | ALDH1A1POLBL3MBTL1MAPK1LMNA | |
| SCHEMBL9584660 | 0.75 | ALDH1A1 (0.63) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL27927350 | 0.75 | KMT2A (0.40) | ALDH1A1POLBNPSR1KMT2AHTT | |
| SCHEMBL28807609 | 0.74 | ALDH1A1 (0.72) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 | |
| SCHEMBL6655554 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBUSP2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1141627-A | Indole derivatives for the treatment of estrogen-related tumors and diseases | MERRELL DOW PHARMA (US) | 1997-01-29 | — | — | CN | disclosed |