Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745444 | 0.81 | HPGD (0.49) | SMN1; SMN2MAPTHPGDLMNAPOLB | |
| SCHEMBL6212063 | 0.78 | PPOX (0.35) | SMN1; SMN2MAPTHPGDLMNAPPOX | |
| SCHEMBL27475224 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2MAPTHPGDLMNATSHR | |
| SCHEMBL27407281 | 0.73 | TP53 (0.35) | SMN1; SMN2MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL27475223 | 0.72 | KDM4E (0.40) | SMN1; SMN2MAPTHPGDLMNAPPOX | |
| SCHEMBL8740973 | 0.70 | GPR17 (0.36) | SMN1; SMN2MAPTHPGDLMNATSHR | |
| SCHEMBL9696585 | 0.68 | ALDH1A1 (0.48) | SMN1; SMN2MAPTLMNAPOLBKMT2A | |
| SCHEMBL27564345 | 0.68 | ELANE (0.46) | SMN1; SMN2MAPTHPGDLMNAKDM4E | |
| SCHEMBL8740982 | 0.68 | NPSR1 (0.38) | SMN1; SMN2MAPTHPGDLMNATSHR | |
| SCHEMBL6215109 | 0.67 | MAPT (0.37) | SMN1; SMN2MAPTHPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143080-A | Method for preparing 7-bicyclic substituted -3-quinone derivative | BAYER AG (DE) | 1997-02-19 | — | — | CN | disclosed |