Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 8/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.47 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382054 | 0.84 | STK4 (0.73) | STK4EGFRERBB2SRCLRRK2 | |
| SCHEMBL7617908 | 0.81 | EGFR (0.51) | EGFRERBB2SRCMAP2K1 | |
| SCHEMBL27460476 | 0.78 | EGFR (0.61) | STK4EGFRERBB2SRCLRRK2 | |
| SCHEMBL27482851 | 0.77 | STK4 (0.56) | STK4EGFRERBB2SRCLRRK2 | |
| SCHEMBL27433614 | 0.77 | STK4 (0.55) | STK4EGFRERBB2SRCLRRK2 | |
| SCHEMBL27432836 | 0.77 | STK4 (0.55) | STK4EGFRERBB2SRCMAP2K1 | |
| SCHEMBL27480999 | 0.77 | STK4 (0.55) | STK4EGFRERBB2SRCMAP2K1 | |
| SCHEMBL6381772 | 0.74 | EGFR (0.56) | STK4EGFRERBB2SRCMAP2K1 | |
| SCHEMBL22419654 | 0.71 | STK4 (1.00) | STK4EGFRERBB2LRRK2 | |
| SCHEMBL4744821 | 0.71 | EGFR (0.55) | STK4EGFRERBB2SRCPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121391-C | Substituted 3-cyano quinolines | AMERICAN CYANAMID CO (US) | 2003-09-17 | — | — | CN | claimed |
| CN-1429126-A | Use of cyanoquinolines for treating or inhibiting colonic polyps | AMERICAN CYANAMID CO (US) | 2003-07-09 | — | — | CN | claimed |
| CN-1259125-A | Substituted 3-cyanoquinolines | AMERICAN CYANAMID CO (US) | 2000-07-05 | — | — | CN | claimed |
| CN-1190197-C | Application of cyanoquinoline in preparing medicine for treating or inhibiting colonic polyp | HEWLETT HOLDINGS CORP (US) | 2005-02-23 | — | — | CN | disclosed |
| CN-1121391-C | Substituted 3-cyano quinolines | AMERICAN CYANAMID CO (US) | 2003-09-17 | — | — | CN | disclosed |
| CN-1429126-A | Use of cyanoquinolines for treating or inhibiting colonic polyps | AMERICAN CYANAMID CO (US) | 2003-07-09 | — | — | CN | disclosed |