Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.61 |
| ▸ | STK4 | Q13043 | 1/20 | 0.59 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382054 | 0.88 | STK4 (0.73) | EGFRERBB2STK4SRCLRRK2 | |
| SCHEMBL27433614 | 0.82 | STK4 (0.55) | EGFRERBB2STK4GAKSRC | |
| SCHEMBL27432836 | 0.82 | STK4 (0.55) | EGFRERBB2STK4SRC | |
| SCHEMBL27480999 | 0.82 | STK4 (0.55) | EGFRERBB2STK4SRC | |
| SCHEMBL27458919 | 0.78 | STK4 (0.55) | EGFRERBB2STK4SRCLRRK2 | |
| SCHEMBL27482851 | 0.77 | STK4 (0.56) | EGFRERBB2STK4SRCLRRK2 | |
| SCHEMBL95052 | 0.76 | EGFR (1.00) | EGFRERBB2STK4GAK | |
| SCHEMBL22419654 | 0.75 | STK4 (1.00) | EGFRERBB2STK4LRRK2 | |
| SCHEMBL6381492 | 0.74 | EGFR (0.71) | EGFRERBB2STK4GAKSRC | |
| SCHEMBL6380499 | 0.73 | EGFR (1.00) | EGFRERBB2GAKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121391-C | Substituted 3-cyano quinolines | AMERICAN CYANAMID CO (US) | 2003-09-17 | — | — | CN | claimed |
| CN-1259125-A | Substituted 3-cyanoquinolines | AMERICAN CYANAMID CO (US) | 2000-07-05 | — | — | CN | claimed |
| CN-1121391-C | Substituted 3-cyano quinolines | AMERICAN CYANAMID CO (US) | 2003-09-17 | — | — | CN | disclosed |