Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233350 | 0.74 | CA2 (0.41) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL23531713 | 0.74 | MCL1 (0.41) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL1548108 | 0.72 | CCR4 (0.41) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL1523258 | 0.72 | CA2 (0.42) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL396243 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3869152 | 0.71 | CA2 (0.41) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL2762829 | 0.67 | PKM (0.35) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL23732206 | 0.67 | DAO (0.57) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL2631260 | 0.65 | KMT2A (0.48) | KMT2ACA2CA1CA9CA4 | |
| SCHEMBL23569829 | 0.65 | MCL1 (0.39) | KMT2ACA2CA1CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158290-C | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | ŵ��Ų�ڿ˹�˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1208417-A | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |