Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046292 | 0.80 | CFTR (0.47) | MAPTCFTRALDH1A1NPSR1LMNA | |
| SCHEMBL6996282 | 0.76 | CES2 (0.50) | MAPTALDH1A1LMNAHTTMAPK1 | |
| SCHEMBL18724910 | 0.73 | CES2 (0.57) | ALDH1A1NPSR1LMNACES2MEN1 | |
| SCHEMBL7000102 | 0.72 | SRD5A2 (0.46) | ALDH1A1CES2CES1KDM4EHPGD | |
| SCHEMBL9657857 | 0.72 | MAPK1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4133046 | 0.71 | KMT2A (0.44) | ALDH1A1CES2CES1KDM4EKMT2A | |
| SCHEMBL5759258 | 0.70 | ALDH1A1 (0.44) | ALDH1A1NPSR1HIF1ACES2CES1 | |
| SCHEMBL14081954 | 0.70 | CES2 (0.50) | MAPTALDH1A1NPSR1LMNACES2 | |
| SCHEMBL29954139 | 0.69 | CFTR (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7001947 | 0.69 | CFTR (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108298-C | Process for preparing substituted chromanol derivatives | PFIZER (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1230954-A | Process for preparing substituted chromanol derivatives and intermediates | PFIZER (US) | 1999-10-06 | — | — | CN | disclosed |